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类风湿关节炎的遗传学

The genetics of rheumatoid arthritis.

作者信息

O'Brien W M

出版信息

Clin Exp Immunol. 1967 Dec;2(Suppl):Suppl:785-802.

Abstract

A first step in understanding the epidemiology of any chronic disease is the separation of heredity and environment. Many workers feel that rheumatoid arthritis (RA) is an inherited disease. This review critically analyses the literature on this subject, and concludes that the available studies give little support to any genetic cause of RA.

摘要

了解任何一种慢性病流行病学的第一步是区分遗传因素和环境因素。许多研究人员认为类风湿性关节炎(RA)是一种遗传性疾病。这篇综述对该主题的文献进行了批判性分析,并得出结论:现有研究几乎没有支持RA任何遗传病因的依据。

引用本文的文献

1
Family history of rheumatoid arthritis: an old concept with new developments.
Nat Rev Rheumatol. 2016 Jun;12(6):335-43. doi: 10.1038/nrrheum.2016.52. Epub 2016 Apr 21.
3
Auto-antibodies in rheumatoid arthritis.
Ir J Med Sci. 1973 Sep;142(5):244-8. doi: 10.1007/BF02950018.
4
Gc (vitamin D binding protein) subtypes in rheumatoid arthritis.
Hum Genet. 1985;70(3):278-80. doi: 10.1007/BF00273457.
6
HLA antigens in Yugoslav population with rheumatoid arthritis.
Clin Rheumatol. 1990 Mar;9(1):48-50. doi: 10.1007/BF02030241.
7
Mixed lymphocyte cultures in rheumatoid arthritis.
J Clin Invest. 1976 May;57(5):1148-57. doi: 10.1172/JCI108382.

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