Papiha S S, Pal B
Hum Genet. 1985;70(3):278-80. doi: 10.1007/BF00273457.
Two hundred and six patients with rheumatoid arthritis were examined for their association with the subtypes of Gc (vitamin D binding protein). In patient groups there is 11% excess of individuals with Gc*2 allele compared to the control group, giving a relative risk of 1.55. This risk increases with the humoral status of the individual. A possible physiological basis between the association of vitamin D binding protein and rheumatoid arthritis is discussed.
对206例类风湿性关节炎患者进行了与Gc(维生素D结合蛋白)亚型相关性的检查。与对照组相比,患者组中携带Gc*2等位基因的个体多出11%,相对风险为1.55。这种风险随着个体的体液状态而增加。文中讨论了维生素D结合蛋白与类风湿性关节炎之间关联的可能生理基础。