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[长期酒精化对大鼠脑电活动及情绪行为的影响]

[Effect of prolonged alcoholization on the cerebral electical activity and emotional behavior of rats].

作者信息

Vorob'eva T M

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 Mar-Apr;27(2):252-61.

PMID:559380
Abstract

Two stages of alcohol intoxication were detected in an experiment on 21 rats during formation of addiction to alcohol. It has been shown that the emotiogenic hypothalamic zones may play the part of trigger mechanisms with infolvement of limbic and neocortical apparatuses. At the same time a different type of integration of addiction to alcohol food is possible, in which the emotiogenic zones do not play the principal part. The late stages of formation of addiction to alcohol are characterized by EEG hypersynchronia with a qualitatively different structure in the periods of abstinence and "saturation" with alcohol. A close connection has been recorded between the mechanisms of emotion, hypersynchronia and behavioral epileptic phenomena.

摘要

在对21只大鼠进行酒精成瘾形成实验过程中,检测到了两个酒精中毒阶段。结果表明,情绪发生性下丘脑区域可能在边缘系统和新皮质结构的参与下发挥触发机制的作用。同时,酒精成瘾与食物成瘾可能存在不同类型的整合,其中情绪发生区域并不起主要作用。酒精成瘾形成的后期阶段,脑电图表现为高度同步化,在戒酒期和酒精“饱和”期其结构存在质的差异。已记录到情绪机制、高度同步化和行为性癫痫现象之间存在密切联系。

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