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儿童精神分裂症的诊断、流行病学及病因学

The diagnosis, epidemiology, and etiology of childhood schizophrenia.

作者信息

Marsh R W

出版信息

Genet Psychol Monogr. 1977 May;95(2):267-330.

PMID:559610
Abstract

About half the Australian population of children who were functioning at a moderate or greater level of intellectual subnormality and who also presented schizophrenic behaviors were surveyed. From more than 300 such cases only 21 were confirmed as schizophrenic. Their average age was seven years eight months, four were girls, and eight had histories of normal physical health. Individual data were collected on antenatal and perinatal factors, childhood health, developmental progress, family history, physical characteristics, neurological signs, biochemical anomalies, and behavioral and psychiatric characteristics. These data sustained the hypotheses that the (a) incidence of the condition is slight, that (b) childhood schizophrenia is the result of a multicausal transactional process; that (c) there is a continuum from organic to functional conditions and that (d) the intellectual potential of these children is generally overrated.

摘要

对澳大利亚约一半智力低于正常水平且有精神分裂症行为表现的儿童进行了调查。在300多例此类病例中,仅有21例被确诊为精神分裂症。他们的平均年龄为7岁8个月,4名为女孩,8名有身体健康正常的病史。收集了关于产前和围产期因素、儿童健康、发育进程、家族史、身体特征、神经体征、生化异常以及行为和精神特征的个体数据。这些数据支持了以下假设:(a) 该病症的发病率较低;(b) 儿童精神分裂症是多因素相互作用过程的结果;(c) 从器质性疾病到功能性疾病存在一个连续体;(d) 这些儿童的智力潜力通常被高估。

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