McNamara J O, Heyman A, Silver D, Mandel M E
Neurology. 1977 Jul;27(7):682-4. doi: 10.1212/wnl.27.7.682.
The results of a retrospective study of patients undergoing carotid endarterectomy for hemispheric and/or nonhemispheric symptoms of transient ischemic attacks are presented. During an approximately 3-year period of follow-up observation, recurrent cerebral ischemia following carotid endarterectomy was two to three times more frequent among patients with nonhemispheric transient ischemia than among those with hemispheric transient ischemia. Patients with symptoms of both hemispheric and nonhemispheric transient ischemia had the highest frequency of transient ischemic attacks and stroke during the follow-up period and also had the greatest surgical morbidity and mortality. The results of this study suggest that carotid endarterectomy has little or no therapeutic value in treating patients with vertebral-basilar ischemia.
本文呈现了一项对因半球性和/或非半球性短暂性脑缺血发作症状而接受颈动脉内膜切除术患者的回顾性研究结果。在大约3年的随访观察期内,非半球性短暂性脑缺血患者颈动脉内膜切除术后复发性脑缺血的发生率是半球性短暂性脑缺血患者的两到三倍。有半球性和非半球性短暂性脑缺血症状的患者在随访期间短暂性脑缺血发作和中风的发生率最高,手术发病率和死亡率也最高。本研究结果表明,颈动脉内膜切除术在治疗椎基底动脉缺血患者方面几乎没有治疗价值。