Rosenthal D, Cossman D, Ledig C B, Callow A D
Arch Surg. 1978 Nov;113(11):1361-4. doi: 10.1001/archsurg.1978.01370230151019.
A review was performed of 114 patients with symptoms of vertebrobasilar insufficiency (VBI) alone, or in combination with carotid territory transient ischemic attacks or carotid territory completed stroke (cCS) with follow-up extending to ten years. The most frequent symptoms of VBI were visual changes (50%), dizziness (31%), and syncope (30%). Patients with symptoms of VBI and arteriographic evidence of intracranial disease, regardless of stump pressure, are at high risk for cerebral ischemia during endarterectomy. At late follow-up, ranging from one to ten years, 63% of the patients were alive; 88% were asymptomatic. Causes of death were mainly cardiac (44%) and stroke (36%), but patients with symptoms of VBI and cCS died earlier and from a second cerebrovascular accident. When a correct preoperative diagnosis was established, carotid endarterectomy produced relief of symptoms in 90% of the patients.
对114例仅患有椎基底动脉供血不足(VBI)症状,或合并颈动脉区短暂性脑缺血发作或颈动脉区完全性卒中(cCS)的患者进行了一项随访长达十年的研究。VBI最常见的症状是视觉改变(50%)、头晕(31%)和晕厥(30%)。有VBI症状且有颅内疾病动脉造影证据的患者,无论残端压力如何,在动脉内膜切除术期间发生脑缺血的风险都很高。在1至10年的后期随访中,63%的患者存活;88%无症状。死亡原因主要是心脏疾病(44%)和卒中(36%),但有VBI和cCS症状的患者死亡更早,且死于第二次脑血管意外。当术前做出正确诊断时,颈动脉内膜切除术使90%的患者症状得到缓解。