Koba T, Yokoyama T, Kaneko M
No To Shinkei. 1977 Jan;29(1):75-80.
In 1967, Fisher named the "one and a half syndrome" for a particular ocular movement which is observed in the lesion of pontine tegmentum, when horizontal movement of one eye is totally disabled and the abducence of another eye is only preserved associating mono-ocular nystagmus in the same eye. Vertical movement and convergence are preserved. We experienced this syndrome in four cases of small localized hematoma of the pontine tegmentum which were all removed under operative microscope. All patients are alive more than 10 months under consciousness and with improved neurological sign. Three of them were probably due to hypertensive hemorrhage and the rest was due to arterio-venous malformation of the pontine tegmentum. Three of them showed this syndrome before operation and observed even after operation. One patient was operated on one and a half hours after the apoplectic attack under semicomatous condition and he improved with this syndrome postoperatively. In most previous reports, this syndrome was noted in severe cases of pontine hematoma or basilar artery thrombosis and they expired soon thereafter. All our cases survived in satisfactory condition and ocular movement could be followed up for a long time. The mechanism of this syndrome was also discussed.
1967年，费希尔将一种特殊的眼球运动命名为“一个半综合征”，这种眼球运动见于脑桥被盖部病变，此时一只眼的水平运动完全丧失，另一只眼的外展仅保留，并伴有该眼的单眼眼球震颤。垂直运动和集合运动保留。我们在4例脑桥被盖部局限性小血肿病例中遇到了这种综合征，所有病例均在手术显微镜下切除。所有患者均存活超过10个月，神志清醒，神经体征改善。其中3例可能因高血压性出血，其余1例因脑桥被盖部动静脉畸形。其中3例术前出现此综合征，术后仍可观察到。1例患者在中风发作一个半小时后处于半昏迷状态下接受手术，术后此综合征有所改善。在大多数既往报道中，此综合征见于脑桥血肿或基底动脉血栓形成的严重病例，此后患者很快死亡。我们所有病例均存活良好，眼球运动可长期随访。本文还讨论了该综合征的机制。
