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“前列腺酸性磷酸酶?”通过在组织培养基中的Ficoll等速梯度中进行速度沉降纯化的上皮细胞、粒细胞、单核细胞、淋巴细胞和血小板中酸性磷酸酶活性的比较。

"Prostatic acid phosphatase?" A comparison of acid phosphatase activities in epithelial cells, granulocytes, monocytes, lymphocytes, and platelets purified by velocity sedimentation in isokinetic gradients of Ficoll in tissue culture medium.

作者信息

Helms S R, Brattain M G, Pretlow T G, Kreisberg J I

出版信息

Am J Pathol. 1977 Sep;88(3):529-38.

Abstract

Numerous investigators have found several substrates and inhibitors to be particularly suited for the demonstration of acid phosphatase of prostatic origin. There has been much controversy over the specificity or lack of specificity of several substrates and inhibitors. We have investigated acid phosphatase activities obtained from several kinds of purified cells. None of the substrates or inhibitors which we studied permitted us to discriminate "prostatic" acid phosphatase from acid phosphatase activities obtained from other kinds of cells.

摘要

许多研究人员发现,有几种底物和抑制剂特别适合用于证明前列腺来源的酸性磷酸酶。关于几种底物和抑制剂的特异性或缺乏特异性,一直存在很多争议。我们研究了从几种纯化细胞中获得的酸性磷酸酶活性。我们研究的底物或抑制剂中,没有一种能让我们将“前列腺”酸性磷酸酶与从其他类型细胞中获得的酸性磷酸酶活性区分开来。

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