Himwich W A, Hall J S, MacArthur W F
Biol Psychiatry. 1977 Aug;12(4):495-505.
The disappearance of alcohol from blood following a single dose is a function of age, but by the time the animals are 90 days old the results are consistent from animal to animal. A single dose given to a pregnant female is distributed between fetus and maternal tissues and fluids, with a portion of the alcohol trapped in the amniotic fluid. Kittens born to mothers receiving alcohol during the last 2 weeks of pregnancy demonstrate hyperactivity, small size with unimpaired growth rate, and slow maturation of the righting reflex. It would require more experimentation to decide whether these changes are due to alcohol withdrawal or to toxic effects of the alcohol per se.
单次给药后酒精从血液中的消失情况是年龄的函数，但当动物90日龄时，不同动物的结果是一致的。给怀孕的雌性动物单次给药后，酒精会分布于胎儿与母体的组织和体液中，一部分酒精会被困在羊水中。在怀孕最后两周接受酒精的母猫所生的小猫表现出多动、体型小但生长速率未受影响以及翻正反射成熟缓慢。要确定这些变化是由于酒精戒断还是酒精本身的毒性作用，还需要更多实验。
