Gooding J M, Corssen G
Anesth Analg. 1977 Sep-Oct;56(5):717-9. doi: 10.1213/00000539-197709000-00021.
Following intravenous injection of 0.3 mg/kg of etomidate, the only noteworthy change in measured cardiovascular parameters was a 10 percent increase in heart rate. This suggests relatively stable cardiovascular response associated with administration of this new nonbarbiturate anesthesia induction agent.