Hereditary renal disease in a mutant strain of rats.
作者信息
Lozzio B B, Chernoff A I, Machado E R, Lozzio C B
出版信息
Science. 1967 Jun 30;156(3783):1742-4. doi: 10.1126/science.156.3783.1742.
PMID:5629323
Abstract
Disease of the kidney developed in breeding stock of Gunn rats. The renal lesion is the result of a new mutation. The genetic defect is inherited as an autosomal dominant trait and is apparently lethal in the homozygous condition. The abnormality manifests itself as a congenital hydronephrosis with related cystic changes in the kidney.
摘要
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