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[急性血管功能不全条件下肾上腺皮质的组织化学和形态计量学变化]

[Histochemical and morphometric changes in the adrenal cortex under conditions of acute vascular insufficiency].

作者信息

Kochubeĭ N M

出版信息

Biull Eksp Biol Med. 1977 May;83(5):615-6.

PMID:884274
Abstract

Morphofunctional changes in the adrenal glands of 50 male cats under experimental vascular insufficiency were studied by means of morphometric, histochemical, and biochemical methods, with a preliminary investigation of the histoenzymatological profile of the adrenal glands in intact animals. A decrease in the adrenal function was revealed five hours after induced hypotony resulting from intravenous injection of arfonade. Adrenal insufficiency, particularly that of the glucocorticosteroid function, under conditions of developing vascular failure can be considered as a peculiar adaptation of the organism to preserve its viability.

摘要

采用形态计量学、组织化学和生物化学方法,对50只实验性血管功能不全雄性猫的肾上腺形态功能变化进行了研究,并对完整动物肾上腺的组织酶学特征进行了初步研究。静脉注射阿方那特诱导低血压5小时后,肾上腺功能出现下降。在血管功能衰竭的情况下,肾上腺功能不全,尤其是糖皮质激素功能不全,可被视为机体维持生存能力的一种特殊适应方式。

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