Reif-Lehrer L, Amos H
Biochem J. 1968 Jan;106(2):425-30. doi: 10.1042/bj1060425.
Hydrocortisone has been found to induce glutamine synthetase activity in chick-embryo retinas in culture. Evidence is presented to show that the hydrocortisone is definitely required for transcription; its requirement for translation has not been ruled out. The possible identity of hydrocortisone with an active component of calf-serum diffusate reported earlier is discussed. The data also indicate that the glutamine synthetase messenger RNA is stable for at least several hours.
已发现氢化可的松可诱导培养的鸡胚视网膜中的谷氨酰胺合成酶活性。有证据表明转录过程绝对需要氢化可的松；其对翻译的需求尚未排除。文中讨论了氢化可的松与先前报道的小牛血清扩散物活性成分可能的一致性。数据还表明谷氨酰胺合成酶信使核糖核酸至少在数小时内是稳定的。
