X-chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro.
作者信息
Martin G R, Epstein C J, Travis B, Tucker G, Yatziv S, Martin D W, Clift S, Cohen S
出版信息
Nature. 1978 Jan 26;271(5643):329-33. doi: 10.1038/271329a0.
DOI:10.1038/271329a0
PMID:563984
Abstract
Evidence is presented that both X chromosomes are genetically active in clonal cultures of undifferentiated female mouse teratocarcinoma stem cells derived from a spontaneous ovarian tumour. As the cells differentiate in vitro one of the X chromosomes becomes inactivated.
摘要
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