特发性肥厚性主动脉瓣下狭窄患者孕期使用普萘洛尔治疗：安全吗？

Propranolol therapy during pregnancy in a patient with idiopathic hypertrophic subaortic stenosis: is it safe?

作者信息

Sabom M B, Curry R C, Wise D E

出版信息

South Med J. 1978 Mar;71(3):328-9. doi: 10.1097/00007611-197803000-00032.

DOI:10.1097/00007611-197803000-00032

Abstract

A case is presented of a low birth weight infant born prematurely with depressed respiration, sinus bradycardia, and hypoglycemia associated with maternal propranolol therapy during pregnancy and up until labor and delivery. The need for caution in the casual use of propranolol during pregnancy in an asymptomatic patient with IHSS and the potential fetal complications are emphasized.

摘要

本文报告了一例低出生体重早产儿，其出生时呼吸抑制、窦性心动过缓及低血糖，这些情况与母亲在孕期直至分娩期间使用普萘洛尔治疗有关。强调了对于患有特发性肥厚性主动脉瓣下狭窄（IHSS）的无症状孕妇在孕期随意使用普萘洛尔需谨慎，以及可能出现的胎儿并发症。