Carlson B E, Andersen B R
JAMA. 1976 Apr 5;235(14):1465-6.
Granulocytes from patients with suspected bacteremia and from dogs with staphylococcal bacteremia were examined by light microscopy for the presence of intracellular inclusions that resembled microorganisms. Quantitative blood cultures were done at the same time. Few granulocytic inclusions were observed during a two-hour screening period even when high levels of bacteremia were present. There was no correlation between the number of inclusions and the quantitative blood culture data. The inclusions appear to be artifacts of the staining procedure. This technique has questionable value in the diagnosis of bacteremia and may be misleading.
对疑似菌血症患者以及患有葡萄球菌菌血症的犬类的粒细胞进行了光学显微镜检查，以寻找类似微生物的细胞内包涵体。同时进行了定量血培养。在两小时的筛查期内，即使存在高水平的菌血症，也仅观察到少量粒细胞包涵体。包涵体数量与定量血培养数据之间无相关性。这些包涵体似乎是染色过程中的人为产物。该技术在菌血症诊断中的价值存疑，可能会产生误导。
