Jarrett R J, Viberti G C, Sayegh H A
Br Med J. 1978 Mar 4;1(6112):548-9. doi: 10.1136/bmj.1.6112.548.
Twenty-eight men were given morning and afternoon oral glucose tolerance tests in 1969 and again in 1975. According to British Diabetic Association criteria all 28 had normal morning values in 1969 but seven had "afternoon diabetes". Four men had diabetic values in the morning in 1975 but only two of these had had afternoon diabetes in 1969. Better prediction of subsequent diabetes was obtained by calculating the area under the morning glucose tolerance curve in 1969. All four men who progressed to diabetes had areas exceeding 1000 units, which distinguished them absolutely from the other 24. They also tended to be more obese, but this was less predictive of subsequent diabetes.
1969年,28名男性接受了上午和下午的口服葡萄糖耐量测试,1975年再次进行测试。根据英国糖尿病协会的标准,1969年这28人上午的测试值均正常,但有7人出现“下午糖尿病”。1975年有4名男性上午的测试值呈糖尿病水平,但其中只有2人在1969年出现过下午糖尿病。通过计算1969年上午葡萄糖耐量曲线下的面积,能更好地预测后续糖尿病情况。所有发展为糖尿病的4名男性的曲线下面积超过1000单位,这使他们与其他24人有了绝对区别。他们往往也更肥胖,但这对后续糖尿病的预测性较差。