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口服葡萄糖耐量的昼夜变化:糖尿病演变的一个可能指标。

Diurnal variation of oral glucose tolerance: a possible pointer to the evolution of diabetes mellitus.

作者信息

Jarrett R J, Keen H

出版信息

Br Med J. 1969 May 10;2(5653):341-4. doi: 10.1136/bmj.2.5653.341.

Abstract

Possible diurnal variation in the blood sugar response to oral glucose was studied by comparing, in the same individuals, the results of oral glucose tolerance tests performed in the morning and the afternoon. In a group of normal individuals the blood sugar levels were significantly higher in the afternoon. In hyperglycaemic individuals the diurnal variation decreased as the blood sugar levels reached during the morning test increased, so that in a group of grossly hyperglycaemic men the mean morning and afternoon tests were almost identical. The causes of this diurnal variation are not known.

摘要

通过在同一组个体中比较其上午和下午进行的口服葡萄糖耐量试验结果,研究了口服葡萄糖后血糖反应可能存在的昼夜变化。在一组正常个体中,下午的血糖水平显著更高。在高血糖个体中,随着上午测试中达到的血糖水平升高,昼夜变化减小,以至于在一组严重高血糖男性中,上午和下午测试的平均值几乎相同。这种昼夜变化的原因尚不清楚。

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