小鼠中的胎儿血红蛋白变体
Fetal hemoglobin variants in mice.
作者信息
Gilman J G, Smithies O
出版信息
Science. 1968 May 24;160(3830):885-6. doi: 10.1126/science.160.3830.885.
PMID:5647833
Abstract
Two strains of mice, DBA and C3H, have a fetal globin polypeptide chain which differs in electrophoretic mobility from the corresponding fetal chain of the C57B1 strain. Mice of the DBA and C3H strains also differ from those of the C57B1 in adult hemoglobin type. Results of backcrossing the (DBA x C57B1) hybrid to the C57B1 suggest that the fetal chain locus and the adult beta-chain locus are closely linked.
摘要
两种品系的小鼠，DBA和C3H，具有一种胎儿珠蛋白多肽链，其电泳迁移率与C57B1品系相应的胎儿链不同。DBA和C3H品系的小鼠在成人血红蛋白类型上也与C57B1品系的小鼠不同。将（DBA×C57B1）杂种与C57B1回交的结果表明，胎儿链基因座和成人β链基因座紧密连锁。
Zotero 插件