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鳄蜥耳蜗内淋巴和细胞内静息电位

Endolymphatic and intracellular resting potential in the alligator lizard cochlea.

作者信息

Weiss T F, Altmann D W, Mulroy M J

出版信息

Pflugers Arch. 1978 Jan 31;373(1):77-84. doi: 10.1007/BF00581152.

DOI:10.1007/BF00581152
PMID:565037
Abstract

Endolymphatic potential (EP) and intracellular resting potentials (RPs) in the cochlea of the alligator lizard were measured with micropipets. The EP (defined as the dc electric potential recorded between the endolymph in scala media and the perilymph in scala tympani or scala vestibuli) had a mean value of +16 mV (in 96 ears). The RPs (defined as the dc potentials recorded between the intracellular and perilymphatic spaces) were different in the distal portion of the cochlear nerve (range to -56 mV, mean of -23 mV in 158 cells) from those in the region of the basilar papilla (range to -154 mV, mean of -73 mV in 623 cells). In identified cells in the region of the basilar papilla, the mean values of RPs of hyaline epithelial cells (-113 mV in 7 cells) and supporting cells (-93 mV in 13 cells) were more negative than of hair cells (-73 mV in 5 cells). Differences in measured RPs could reflect differences in the resting potentials of these cells and/or their source resistances. RPs measured in the basilar papilla of the alligator lizard are compared with those obtained in other vertebrate hair cell organs.

摘要

用微吸管测量了鳄蜥耳蜗内的内淋巴电位(EP)和细胞内静息电位(RP)。EP(定义为在中阶内淋巴与鼓阶或前庭阶外淋巴之间记录的直流电势)的平均值为+16 mV(96只耳朵)。RP(定义为在细胞内和外淋巴间隙之间记录的直流电势)在蜗神经远端部分(范围为-56 mV,158个细胞的平均值为-23 mV)与基底乳头区域的RP不同(范围为-154 mV,623个细胞的平均值为-73 mV)。在基底乳头区域的已识别细胞中,透明上皮细胞(7个细胞中为-113 mV)和支持细胞(13个细胞中为-93 mV)的RP平均值比毛细胞(5个细胞中为-73 mV)更负。测量的RP差异可能反映了这些细胞静息电位及其源电阻的差异。将鳄蜥基底乳头中测量的RP与其他脊椎动物毛细胞器官中获得的RP进行了比较。

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引用本文的文献

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Receptor potentials of lizard hair cells with free-standing stereocilia: responses to acoustic clicks.具有独立静纤毛的蜥蜴毛细胞的感受器电位:对声点击的反应。
J Physiol. 1983 Feb;335:699-721. doi: 10.1113/jphysiol.1983.sp014559.
2
Receptor potentials of lizard cochlear hair cells with free-standing stereocilia in response to tones.具有独立静纤毛的蜥蜴耳蜗毛细胞对音调的感受器电位。
J Physiol. 1983 Dec;345:205-40. doi: 10.1113/jphysiol.1983.sp014975.
3
Sensory transduction and neuronal transmission as related to ultrastructure and encoding of information in different labyrinthine receptor systems of vertebrates.

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The membrane potential of Ehrlich ascites tumor cells microelectrode measurements and their critical evaluation.艾氏腹水瘤细胞膜电位的微电极测量及其临界评价。
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