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大丽轮枝菌从(+)-蔷薇色酸、1,8-二羟基萘、儿茶酚和L-3,4-二羟基苯丙氨酸形成的黑色素的超微结构和化学区分

Ultrastructural and chemical distinction of melanins formed by Verticillium dahliae from (+)-scytalone, 1,8-dihydroxynaphthalene, catechol, and L-3,4-dihydroxyphenylalanine.

作者信息

Wheeler M H, Tolmsoff W J, Bell A A, Mollenhauer H H

出版信息

Can J Microbiol. 1978 Mar;24(3):289-97. doi: 10.1139/m78-049.

DOI:10.1139/m78-049
PMID:565670
Abstract

Microsclerotia of three melanin-deficient mutants of Verticillium dahliae formed malanin from (+)-scytalone, 1,8-dihydroxynaphthalene, catechol, and L-3,4-dihydroxyphenylalanine. The melanins formed from (+)-scytalone or 1,8-dihydroxynaphthalene resembled wild-type melanin chemically and ultrastructurally, whereas the melanins formed from catechol and L-3,4-dihydroxyphenlalanine were different. This suggests that scytalone and 1,8-dihydroxynaphthalene but no catechol or L-3,4-dihydroxyphenylalanine are natural intermediates of melanin biosynthesis in V. dahliae.

摘要

大丽轮枝菌三个黑色素缺陷型突变体的微菌核可利用(+)-紫草酮、1,8-二羟基萘、儿茶酚和L-3,4-二羟基苯丙氨酸形成黑色素。由(+)-紫草酮或1,8-二羟基萘形成的黑色素在化学和超微结构上类似于野生型黑色素,而由儿茶酚和L-3,4-二羟基苯丙氨酸形成的黑色素则有所不同。这表明紫草酮和1,8-二羟基萘而非儿茶酚或L-3,4-二羟基苯丙氨酸是大丽轮枝菌黑色素生物合成的天然中间体。

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