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抗鸽羽花提取物抗体:鸽迷肺中的另一种抗原。

Antibody against a pigeon bloom-extract: a further antigen in pigeon fanciers' lung.

作者信息

Banham S W, McKenzie H, McSharry C, Lynch P P, Boyd G

出版信息

Clin Allergy. 1982 Mar;12(2):173-8. doi: 10.1111/j.1365-2222.1982.tb01636.x.

DOI:10.1111/j.1365-2222.1982.tb01636.x
PMID:7074821
Abstract

Pigeon bloom, a waxy powder which coats the feathers of racing pigeons, has been investigated as a potential antigen in pigeon fanciers' lung. Precipitins to a soluble bloom-extract were demonstrated in fifty-nine of ninety-seven people studied at two Scottish-pigeon shows, whilst precipitins to pigeon serum were found in thirty-seven. A radioimmunoassay was developed to allow an estimation of the intensity of antibody response to this antigen in nineteen pigeon fanciers being investigated for pigeon fanciers' lung. The mean antibody level to bloom extract was significantly higher (P less than 0.05) in those with acute symptoms compared to those with less severe symptoms. Pigeon bloom is a highly antigenic material and provides an alternative to pigeon droppings as a source for the inhalant antigens regularly encountered by those keeping pigeons.

摘要

鸽羽粉是一种覆盖在赛鸽羽毛上的蜡质粉末,已被作为信鸽饲养者肺病的一种潜在抗原进行研究。在两场苏格兰信鸽展览会上,对97人进行的研究中,有59人对可溶性羽粉提取物产生了沉淀素,而37人对鸽血清产生了沉淀素。开发了一种放射免疫测定法,以评估19名因信鸽饲养者肺病正在接受调查的信鸽饲养者对该抗原的抗体反应强度。与症状较轻的人相比,有急性症状的人对羽粉提取物的平均抗体水平显著更高(P小于0.05)。鸽羽粉是一种高度抗原性物质,作为饲养鸽子的人经常接触的吸入性抗原来源,它可替代鸽粪。

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Antibody against a pigeon bloom-extract: a further antigen in pigeon fanciers' lung.抗鸽羽花提取物抗体:鸽迷肺中的另一种抗原。
Clin Allergy. 1982 Mar;12(2):173-8. doi: 10.1111/j.1365-2222.1982.tb01636.x.
2
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Precipitating antibodies against pigeon bloom antigens as a specific and sensitive measure of pigeon exposure.抗鸽羽粉尘抗原沉淀抗体作为检测鸽子接触情况的一种特异且灵敏的方法。
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Pigeon fanciers' lung: the mucin antigen is present in pigeon droppings and pigeon bloom.养鸽者肺:粘蛋白抗原存在于鸽粪和鸽羽粉尘中。
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IgG subclass responses to pigeon intestinal mucin are related to development of pigeon fanciers' lung.对鸽肠道粘蛋白的IgG亚类反应与养鸽人肺的发展有关。
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Characteristics of antibody responses in Pigeon Fanciers' Lung.鸽爱好者肺中的抗体反应特征。
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引用本文的文献

1
Bird fancier's lung: a state-of-the-art review.禽鸟爱好者肺:最新综述。
Clin Rev Allergy Immunol. 2012 Aug;43(1-2):69-83. doi: 10.1007/s12016-011-8282-y.
2
Takes your breath away--the immunology of allergic alveolitis.令人惊叹——过敏性肺泡炎的免疫学
Clin Exp Immunol. 2002 Apr;128(1):3-9. doi: 10.1046/j.1365-2249.2002.01849.x.
3
Detection of specific antibodies to pigeon serum and bloom antigens by enzyme linked immunosorbent assay in pigeon breeder's disease.采用酶联免疫吸附测定法检测鸽饲养者病中针对鸽血清和布鲁姆抗原的特异性抗体。
Occup Environ Med. 2000 Mar;57(3):159-64. doi: 10.1136/oem.57.3.159.
4
Pigeon fanciers' lung: effects of smoking on serum and salivary antibody responses to pigeon antigens.鸽迷肺:吸烟对血清及唾液中针对鸽抗原的抗体反应的影响。
Clin Exp Immunol. 1998 Aug;113(2):166-72. doi: 10.1046/j.1365-2249.1998.00653.x.
5
Bird fancier's disease.养鸟者病
Br Med J (Clin Res Ed). 1983 Oct 29;287(6401):1239-40. doi: 10.1136/bmj.287.6401.1239.
6
Pigeon breeders' lung: pigeon intestinal mucin, an antigen distinct from pigeon IgA.鸽饲养者肺:鸽肠粘蛋白,一种不同于鸽IgA的抗原。
Clin Exp Immunol. 1991 Sep;85(3):453-8. doi: 10.1111/j.1365-2249.1991.tb05748.x.