Banham S W, McKenzie H, McSharry C, Lynch P P, Boyd G
Clin Allergy. 1982 Mar;12(2):173-8. doi: 10.1111/j.1365-2222.1982.tb01636.x.
Pigeon bloom, a waxy powder which coats the feathers of racing pigeons, has been investigated as a potential antigen in pigeon fanciers' lung. Precipitins to a soluble bloom-extract were demonstrated in fifty-nine of ninety-seven people studied at two Scottish-pigeon shows, whilst precipitins to pigeon serum were found in thirty-seven. A radioimmunoassay was developed to allow an estimation of the intensity of antibody response to this antigen in nineteen pigeon fanciers being investigated for pigeon fanciers' lung. The mean antibody level to bloom extract was significantly higher (P less than 0.05) in those with acute symptoms compared to those with less severe symptoms. Pigeon bloom is a highly antigenic material and provides an alternative to pigeon droppings as a source for the inhalant antigens regularly encountered by those keeping pigeons.
鸽羽粉是一种覆盖在赛鸽羽毛上的蜡质粉末,已被作为信鸽饲养者肺病的一种潜在抗原进行研究。在两场苏格兰信鸽展览会上,对97人进行的研究中,有59人对可溶性羽粉提取物产生了沉淀素,而37人对鸽血清产生了沉淀素。开发了一种放射免疫测定法,以评估19名因信鸽饲养者肺病正在接受调查的信鸽饲养者对该抗原的抗体反应强度。与症状较轻的人相比,有急性症状的人对羽粉提取物的平均抗体水平显著更高(P小于0.05)。鸽羽粉是一种高度抗原性物质,作为饲养鸽子的人经常接触的吸入性抗原来源,它可替代鸽粪。