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Dominance of colchicine resistance in hybrid CHO cells.

作者信息

Ling V, Baker R M

出版信息

Somatic Cell Genet. 1978 Mar;4(2):193-200. doi: 10.1007/BF01538984.

DOI:10.1007/BF01538984
PMID:566474
Abstract

Intraspecific hybrids of colchicine-sensitive with colchicine-resistant (CHR) Chinese hamster ovary cells were constructed, using six different colchicine-resistant clones from two independent series. In each instance, colchicine resistance was expressed in an incompletely dominant manner. Some hybrid clones were examined further for the expression of the pleiotropic CHR phenotype and for the cell surface P glycoprotein. These features of the colchicine-resistant phenotype were also expressed coordinately.

摘要

相似文献

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Dominance of colchicine resistance in hybrid CHO cells.
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