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患有酒精胚胎病的儿童淋巴细胞中交换型畸变无升高。

No elevation of exchange type aberrations in lymphocytes of children with alcohol embryopathy.

作者信息

Obe G, Majewski F

出版信息

Hum Genet. 1978 Jul 12;43(1):31-6. doi: 10.1007/BF00396475.

DOI:10.1007/BF00396475
PMID:566716
Abstract

The lymphocyte chromosomes from 23 children with the 'fetal alcohol syndrome' or 'alcohol embryopathy' (AE) were analyzed with respect to exchange type aberrations. These aberrations were not more frequent in AE than in controls. The possibility that AE results from unspecific suppression of RNA and consequently of protein synthesis in the developing embryo is discussed.

摘要

对23名患有“胎儿酒精综合征”或“酒精胚胎病”（AE）的儿童的淋巴细胞染色体进行了交换型畸变分析。这些畸变在AE患儿中并不比对照组更常见。文中讨论了AE是由发育中胚胎的RNA非特异性抑制以及由此导致的蛋白质合成抑制引起的可能性。

相似文献

1
No elevation of exchange type aberrations in lymphocytes of children with alcohol embryopathy.患有酒精胚胎病的儿童淋巴细胞中交换型畸变无升高。
Hum Genet. 1978 Jul 12;43(1):31-6. doi: 10.1007/BF00396475.
2
Furrows and dermal ridges of the hand in patients with alcohol embryopathy.酒精胚胎病患者手部的沟纹和皮嵴
Hum Genet. 1978 Jun 27;42(3):307-14. doi: 10.1007/BF00291311.
3
Alcohol embryopathy and diabetic fetopathy in the same newborn.同一新生儿中的酒精胚胎病和糖尿病胎儿病。
Helv Paediatr Acta. 1979 May;34(2):135-9.
4
[Abnormalities caused by alcohol].[酒精所致异常]
Hippokrates. 1974 Nov;45(4):496-7.
5
[Alcoholic embryopathy].
Orv Hetil. 1977 Feb 27;118(9):504-7.
6
[Signs of alcoholic embryopathy diagnosed in childhood].
Orv Hetil. 1978 Nov 26;119(48):2923-9.
7
[Incidence and pathogenesis of alcohol embryopathy].[酒精性胚胎病的发病率与发病机制]
Monatsschr Kinderheilkd (1902). 1978 May;126(5):284-5.
8
[Fetal alcohol syndrome].[胎儿酒精综合征]
Ned Tijdschr Geneeskd. 1979 Jul 21;123(29):1276-9.
9
Fetal valproate embryopathy in twins: genetic modification of the response to a teratogen.
Birth Defects Orig Artic Ser. 1996;30(1):401-5.
10
[Alcoholic embryopathy. The syndrome of embryonic damage due to excessive alcohol consumption during pregnancy].
Cesk Pediatr. 1978 Sep;33(9):540-2.

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Phases in the drinking history of alcoholics.酗酒者饮酒史的阶段。
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MECHANISMS OF ISOIMMUNIZATION. I. THE TRANSPLACENTAL PASSAGE OF FETAL ERYTHROCYTES IN HOMOSPECIFIC PREGNANCIES.同种免疫的机制。一、同种妊娠中胎儿红细胞的经胎盘通道。
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Genetics. 1969;61(1):Suppl:319-27.
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Equilibrium variations in the redundancy of rDNA in Drosophila melanogaster.黑腹果蝇核糖体DNA冗余度的平衡变化
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[Fetomaternal transfusion of blood lymphocytes and identification of the sex of the fetus].[母胎间输血的淋巴细胞及胎儿性别鉴定]
Ann Genet. 1971 Jun;14(2):133-7.
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[Chromosome studies in persons treated with anticonvulsant drugs].[接受抗惊厥药物治疗者的染色体研究]
Humangenetik. 1972;16(3):209-16. doi: 10.1007/BF00273466.
8
Ethanol and acetaldehyde in the milk and peripheral blood of lactating women after ethanol administration.乙醇摄入后哺乳期妇女乳汁及外周血中的乙醇和乙醛
J Obstet Gynaecol Br Commonw. 1974 Jan;81(1):84-6.
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The human leukocyte test system. I. DNA synthesis and mitoses in PHA-stimulated 2-day cultures.人类白细胞检测系统。I. 植物血凝素刺激的2日龄培养物中的DNA合成与有丝分裂。
Mutat Res. 1974 May;23(2):279-81.
10
Outcome in offspring of chronic alcoholic women.慢性酗酒女性后代的结局
Lancet. 1974 Jun 1;1(7866):1076-8. doi: 10.1016/s0140-6736(74)90555-8.