患有酒精胚胎病的儿童淋巴细胞中交换型畸变无升高。
No elevation of exchange type aberrations in lymphocytes of children with alcohol embryopathy.
作者信息
Obe G, Majewski F
出版信息
Hum Genet. 1978 Jul 12;43(1):31-6. doi: 10.1007/BF00396475.
PMID:566716
Abstract
The lymphocyte chromosomes from 23 children with the 'fetal alcohol syndrome' or 'alcohol embryopathy' (AE) were analyzed with respect to exchange type aberrations. These aberrations were not more frequent in AE than in controls. The possibility that AE results from unspecific suppression of RNA and consequently of protein synthesis in the developing embryo is discussed.
摘要
对23名患有“胎儿酒精综合征”或“酒精胚胎病”（AE）的儿童的淋巴细胞染色体进行了交换型畸变分析。这些畸变在AE患儿中并不比对照组更常见。文中讨论了AE是由发育中胚胎的RNA非特异性抑制以及由此导致的蛋白质合成抑制引起的可能性。
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No elevation of exchange type aberrations in lymphocytes of children with alcohol embryopathy.患有酒精胚胎病的儿童淋巴细胞中交换型畸变无升高。
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