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酒精胚胎病患者手部的沟纹和皮嵴

Furrows and dermal ridges of the hand in patients with alcohol embryopathy.

作者信息

Tillner I, Majewski F

出版信息

Hum Genet. 1978 Jun 27;42(3):307-14. doi: 10.1007/BF00291311.

Abstract

Palmar creases and dermal ridge patterns of 34 patients with alcohol embryopathy are compared with 470 healthy individuals. In alcohol embryopathy several typical deviations were noted. Palmar Creases. The interdigital part of the distal palmar crease is generally sharply bent, the proximal transverse crease is hypoplastic or missing, the thenar crease is commonly well marked. Simian creases and bridged palmar creases are more common in patients with alcohol embryopathy than in healthy individuals. Ridge Patterns of the Palm. The main line D coming from triradius d in patients with alcohol embryopathy mostly shows a low type of ending in the fourth interdigital area; in this area loops are twice as common as in healthy individuals. Patterns of the Fingertips. No deviations were noted in the distribution of whorls and loops, but virtually no arches were observed in patients with alcohol embryopathy. These anomalies suggest embryonic damage in the twelfth week of gestation.

摘要

对34例酒精性胚胎病患者的掌纹和皮嵴纹与470名健康个体进行了比较。在酒精性胚胎病中,发现了几种典型的异常情况。掌纹:远侧掌纹的指间部分通常急剧弯曲,近侧横掌纹发育不全或缺失,鱼际纹通常很明显。猿线和桥状掌纹在酒精性胚胎病患者中比在健康个体中更常见。手掌的嵴纹:酒精性胚胎病患者来自三叉点d的主线D在第四指间区域大多呈低类型终点;在该区域,箕形纹的出现频率是健康个体的两倍。指尖纹:在涡形纹和箕形纹的分布上未发现异常,但酒精性胚胎病患者几乎未观察到弓形纹。这些异常表明妊娠第12周时胚胎受到了损害。

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