Obara S
J Gen Physiol. 1968 Aug;52(2):363-86. doi: 10.1085/jgp.52.2.363.
The generator potential of both slowly and rapidly adapting crayfish stretch receptor cells can still be elicited by mechanical stimuli when all the Na of the bathing medium is replaced by various organic cations. In the presence of tris(hydroxymethyl)aminomethane (Tris), the generator potential is particularly large, about 30-50 % of that in the control saline, while spike electrogenesis of the cell is abolished. Persistence of the generator response is not due to retention of Na by a diffusion barrier, and ionic contributions to the electrogenesis by Ca and Cl can also be excluded. Thus, whereas the electrogenesis of the generator membrane must be due to an increased permeability to monovalent cations, the active receptor membrane appears to be less selective for different monovalent cations than is the receptor component of some other cells, or the conductile component of the stretch receptor neuron.
当用各种有机阳离子取代浸浴介质中的所有钠离子时，缓慢适应和快速适应的小龙虾伸展感受器细胞的发生器电位仍可由机械刺激诱发。在存在三（羟甲基）氨基甲烷（Tris）的情况下，发生器电位特别大，约为对照盐溶液中的30%-50%，而细胞的锋电位电活动则被消除。发生器反应的持续存在并非由于扩散屏障保留了钠离子，钙和氯对电活动的离子贡献也可排除。因此，虽然发生器膜的电活动必定是由于对单价阳离子的通透性增加，但活性感受器膜对不同单价阳离子的选择性似乎比其他一些细胞的感受器成分或伸展感受器神经元的传导成分要低。
