Reuben J P, Brandt P W, Girardier L, Grundfest H
Science. 1967 Mar 10;155(3767):1263-6. doi: 10.1126/science.155.3767.1263.
Membrane of crayfish muscle fibers becomes selectively permeable to sodium when the calcium concentration of the bathing medium is reduced. Removal of calcium or its reduction below 1 or 2 millimole per liter causes large transient depolarizations up to 70 millivolts in amplitude. They resemble pro longed action potentials and occur only in the presence of sodium. The responses are abolished when tris(hydroxymethyl)aminomethane or lithium is substituted for sodium, and are blocked by tetrodotoxin even in the presence of sodium.
当浸浴介质中的钙浓度降低时，小龙虾肌肉纤维膜对钠会变得具有选择性通透性。去除钙或将其浓度降低至每升1或2毫摩尔以下会导致幅度高达70毫伏的大幅瞬时去极化。它们类似于延长的动作电位，并且仅在有钠存在时才会出现。当用三（羟甲基）氨基甲烷或锂替代钠时，这些反应就会消失，并且即使在有钠存在的情况下，它们也会被河豚毒素阻断。
