Swanson J A, Jacoby C G, Sherman B M, Dolan K D, Chapler F K
Obstet Gynecol. 1978 Jul;52(1):67-72.
We have reviewed our experience in the radiographic and ophthalmologic evaluation of 1001 patients with symptoms suggesting the presence of a pituitary, prolactin-secreting adenoma. Twenty-seven patients had abnormal or suspicious radiographic examination of the sella turcica. Twenty-two of those had hyperprolactinemia. In only one instance was an abnormality noted on polytomography that was not seen on a conventional four-view study of the skull. Based on these findings, a four-view plain conventional radiographic assessment of the skull suffices as a screening procedure in patients with amenorrhea, galactorrhea, or both. Thin section tomography should be reserved to more thoroughly evaluate those patients with elevated serum prolactin concentrations and/or abnormal conventional radiographs. We found visual field testing to be of little value as an initial screening procedure in these patients.
我们回顾了对1001例有垂体泌乳素分泌腺瘤症状患者的放射学和眼科评估经验。27例患者蝶鞍的放射学检查异常或可疑。其中22例有高泌乳素血症。仅1例在断层摄影中发现的异常在颅骨常规四视图检查中未被发现。基于这些发现，对于有闭经、溢乳或两者皆有的患者，颅骨常规四视图平片放射学评估足以作为筛查程序。薄层断层扫描应留作更全面评估血清泌乳素浓度升高和/或常规放射片异常的患者。我们发现视野检查作为这些患者的初始筛查程序价值不大。
