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培养的哺乳动物细胞中DNA的生长点

Growing points of DNA in cultured mammalian cells.

作者信息

Coleman J R, Okada S

出版信息

Biophys J. 1968 Oct;8(10):1098-103. doi: 10.1016/S0006-3495(68)86541-5.

DOI:10.1016/S0006-3495(68)86541-5
PMID:5679391
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1367657/
Abstract

A fraction of DNA, known to be replicating, was examined in the electron microscope. Characteristic branch points were identified as sites at which replication had been taking place. No localized strand separations, nor other structural alterations were discernible at these points.

摘要

一小部分已知正在复制的DNA在电子显微镜下进行了检查。特征性分支点被确定为复制发生的位点。在这些点上没有观察到局部链分离或其他结构改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5d5/1367657/110c6ad60a7f/biophysj00694-0047-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5d5/1367657/110c6ad60a7f/biophysj00694-0047-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5d5/1367657/110c6ad60a7f/biophysj00694-0047-a.jpg

相似文献

1
Growing points of DNA in cultured mammalian cells.培养的哺乳动物细胞中DNA的生长点
Biophys J. 1968 Oct;8(10):1098-103. doi: 10.1016/S0006-3495(68)86541-5.
2
Electron microscopic studies of replicating SV 40 DNA.对正在复制的猿猴空泡病毒40(SV 40)DNA的电子显微镜研究。
Acta Med Okayama (1952). 1971 Aug;25(4):237-43.
3
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4
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RNA synthesis in relation to DNA replication in synchronized Chinese hamster cell cultures.同步化的中国仓鼠细胞培养物中与DNA复制相关的RNA合成
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本文引用的文献

1
THE DETERMINATION OF MAGNIFICATION IN THE ELECTRON MICROSCOPE. II. MEANS FOR THE DETERMINATION OF MAGNIFICATION.
Lab Invest. 1965 Jun;14:880-91.
2
The bacterial chromosome and its manner of replication as seen by autoradiography.通过放射自显影观察到的细菌染色体及其复制方式。
J Mol Biol. 1963 Mar;6:208-13. doi: 10.1016/s0022-2836(63)80070-4.
3
Electron stains. II: Electron microscopic studies on the visibility of stained DNA molecules.电子染色。II:关于染色DNA分子可见性的电子显微镜研究。
J Mol Biol. 1961 Dec;3:717-26. doi: 10.1016/s0022-2836(61)80076-4.
4
Genetics of human cell lines. III. Incorporation of 5-bromo- and 5-iododeoxyuridine into the deoxyribonucleic acid of human cells and its effect on radiation sensitivity.人类细胞系的遗传学。III. 5-溴脱氧尿苷和5-碘脱氧尿苷掺入人类细胞的脱氧核糖核酸及其对辐射敏感性的影响。
J Exp Med. 1960 Sep 1;112(3):509-31. doi: 10.1084/jem.112.3.509.
5
Electron microscopy of unbroken DNA molecules.完整DNA分子的电子显微镜检查。
J Mol Biol. 1961 Jun;3:263-6. doi: 10.1016/s0022-2836(61)80067-3.
6
Size and structure of the Mycoplasma hominis H39 chromosome.人型支原体H39染色体的大小与结构。
J Mol Biol. 1967 Jan 28;23(2):191-9. doi: 10.1016/s0022-2836(67)80026-3.
7
The arrangement of information in DNA molecules.DNA分子中信息的排列。
J Gen Physiol. 1966 Jul;49(6):143-69. doi: 10.1085/jgp.49.6.143.
8
Replicating units (replicons) of DNA in cultured mammalian cells.培养的哺乳动物细胞中DNA的复制单位(复制子)。
Biophys J. 1968 May;8(5):650-64. doi: 10.1016/S0006-3495(68)86513-0.
9
Enzymatic mechanisms of DNA replication.DNA复制的酶促机制。
J Gen Physiol. 1966 Jul;49(6):59-79. doi: 10.1085/jgp.49.6.59.