DNA分子中信息的排列。
The arrangement of information in DNA molecules.
作者信息
Thomas C A
出版信息
J Gen Physiol. 1966 Jul;49(6):143-69. doi: 10.1085/jgp.49.6.143.
Abstract
The anatomy of DNA molecules isolated from mature bacteriophage is reviewed. These molecules are linear, duplex DNA consisting mainly of uninterrupted polynucleotide chains. Certain phage (T5 and PB) contain four specifically located interruptions. While the nucleotide sequence of most of these molecules is unique (T5, T3, T7, lambda), some are circular permutations of each other (T2, T4, P22). Partial degradation of these DNA molecules by exonuclease III predisposes some of them to form circles upon annealing, but indicating they are terminally redundant.
摘要
本文综述了从成熟噬菌体中分离出的DNA分子的结构。这些分子是线性双链DNA，主要由不间断的多核苷酸链组成。某些噬菌体（T5和PB）含有四个特定位置的间隔。虽然这些分子中的大多数核苷酸序列是独特的（T5、T3、T7、λ），但有些是彼此的环状排列（T2、T4、P22）。核酸外切酶III对这些DNA分子的部分降解使其中一些分子在退火时易于形成环状，但表明它们是末端冗余的。
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