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使用噻苯达唑控制小鼠体内的蛲虫

Control of oxyurids in mice using thiabendazole.

作者信息

MacArthur J A, Wood M

出版信息

Lab Anim. 1978 Jul;12(3):141-3. doi: 10.1258/002367778780936304.

Abstract

Mice with a natural infection of Syphacia obvelata and Aspiculuris tetraptera were continuously medicated with 0.1% thiabendazole in the diet. No oxyurids were found in test animals after 24 days of treatment though control animals remained infected. Growth rates in treated animals increased. 2 generations of mice were studied and, although overall production fell by 1.45%, the use of this drug in total eradication of the worms is suggested.

摘要

自然感染有微小膜壳绦虫和四翼无刺线虫的小鼠,在饮食中持续添加0.1%的噻苯达唑进行药物治疗。治疗24天后,试验动物体内未发现蛲虫,而对照动物仍受感染。治疗组动物的生长速率有所提高。对两代小鼠进行了研究,尽管总体产量下降了1.45%,但仍建议使用这种药物来彻底根除蠕虫。

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