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[小型实验动物的蛲虫感染及其用伊维菌素进行的控制]

[Oxyurid infestation of small laboratory animals and its control with ivermectin].

作者信息

Hasslinger M A, Wiethe T

出版信息

Tierarztl Prax. 1987;15(1):93-7.

PMID:3590171
Abstract

Investigations on parasitic infestations in laboratory animal stocks under different keeping conditions were carried out by fecal sample examination. Only barrier-kept mice and rats proved to be free of infections. Under semi-open or conventionally keeping conditions mice were infected with Aspiculuris tetraptera and Syphacia obvelata (max. 94.7 + 69.7%), rats with A. tetraptera and S. muris (48.6 + 94.9%), and hamsters and mongolian jirds with S. obvelata (26.6 and 16%, respectively). Ivermectin, added to the drinking water for the elimination of murine oxyurids, over a 24-hour period, in a dosage of 1.0 (males) and 1.6 mg/kg body weight (females), proved to be highly effective against A. tetraptera; the treatment of S. obvelata-infections requires a dosage correction.

摘要

通过粪便样本检查,对处于不同饲养条件下的实验动物种群中的寄生虫感染情况进行了调查。结果表明,只有饲养在屏障环境中的小鼠和大鼠未被感染。在半开放或常规饲养条件下,小鼠感染了四翼无钩线虫和奥氏管状线虫(最高感染率为94.7 + 69.7%),大鼠感染了四翼无钩线虫和鼠管状线虫(48.6 + 94.9%),仓鼠和长爪沙鼠感染了奥氏管状线虫(分别为26.6%和16%)。伊维菌素添加到饮用水中,以消除小鼠蛲虫,在24小时内,雄性剂量为1.0毫克/千克体重,雌性剂量为1.6毫克/千克体重,结果证明对四翼无钩线虫非常有效;治疗奥氏管状线虫感染需要调整剂量。

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