豚鼠同基因品系中对结肠毛圆线虫免疫力的细胞转移。IV. 感染和未感染豚鼠小肠中免疫淋巴细胞的定位
The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea-pig. IV. The localization of immune lymphocytes in small intestine in infected and non-infected guinea-pigs.
作者信息
Dineen J K, Ronai P M, Wagland B M
出版信息
Immunology. 1968 Nov;15(5):671-9.
Abstract
Immune and non-immune mesenteric lymph node and Peyer's patch cells were labelled with Cr and injected intravenously into infected and non-infected syngeneic guinea-pigs (Heston strain). From the distribution of the radioactive label in the small intestine (the site of infection of ) it was concluded that immune lymphocytes: (1) preferentially localize or home in' on the infection, (2) come into intimate contact with the parasite in the epithelium, and (3) rapidly undergo allergic death' or lysis at the site of infection.
摘要
将免疫和非免疫的肠系膜淋巴结及派伊尔结细胞用铬标记后，静脉注射到受感染和未受感染的同基因豚鼠（赫斯顿品系）体内。从小肠（感染部位）放射性标记的分布情况得出结论：免疫淋巴细胞：（1）优先定位或“归巢”于感染部位，（2）在上皮细胞中与寄生虫密切接触，（3）在感染部位迅速发生“过敏性死亡”或裂解。
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