The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea-pig. IV. The localization of immune lymphocytes in small intestine in infected and non-infected guinea-pigs.

Immune and non-immune mesenteric lymph node and Peyer's patch cells were labelled with Cr and injected intravenously into infected and non-infected syngeneic guinea-pigs (Heston strain). From the distribution of the radioactive label in the small intestine (the site of infection of ) it was concluded that immune lymphocytes: (1) preferentially localize or home in' on the infection, (2) come into intimate contact with the parasite in the epithelium, and (3) rapidly undergo allergic death' or lysis at the site of infection.