肿瘤结合免疫球蛋白。肿瘤细胞对放射性碘标记的抗免疫球蛋白试剂的体外固定作用。
Tumour-bound immunoglobulins. The in vitro fixation of radioiodine-labelled anti-immunoglobulin reagents by tumour cells.
作者信息
Witz I P, Kinamon S, Ran M, Klein G
出版信息
Clin Exp Immunol. 1974 Mar;16(3):321-33.
Radioiodine-labelled globulins from antisera directed against mouse immunoglobulin, are fixed by cells of various mouse ascites tumours, thus indicating that the cells are coated with immunoglobulins. The amounts of tumour-bound immunoglobulin in the tumour-bearing animal increase as the time interval between tumour inoculation and the harvest of tumour cells increases. Tumour cells from mice which had been irradiated prior to the tumour inoculation are associated, in general, with lower amounts of immunoglobulin than tumour cells from unirradiated mice.
来自针对小鼠免疫球蛋白的抗血清的放射性碘标记球蛋白，可被各种小鼠腹水肿瘤的细胞固定，这表明这些细胞被免疫球蛋白包被。荷瘤动物体内肿瘤结合免疫球蛋白的量随着肿瘤接种与肿瘤细胞收获之间的时间间隔增加而增加。在肿瘤接种前接受过照射的小鼠的肿瘤细胞，一般来说，与未照射小鼠的肿瘤细胞相比，其免疫球蛋白含量较低。
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