Okagaki T, Ishida T, Hilgers R D
Cancer. 1976 May;37(5):2306-20. doi: 10.1002/1097-0142(197605)37:5<2306::aid-cncr2820370521>3.0.co;2-o.
A malignant tumor arising in the upper lateral vaginal mucosa in a 24-year-old white woman, hitherto undescribed in the literature, was studied by light and electron microscopy. The main part of the tumor was epithelioid, forming a tubular or acinar pattern. At the periphery, the tumor cells were more spindly and formed sheets resembling fibrosarcoma. The tumor cells contained occasional material positive for mucicarmine, alcian blue, and PAS stains, and the nests of the cells forming acini were surrounded by reticulin fibers. The tumor ultrastructure consisted of a single type of cell with large cytoplasmic vacuoles and occasional perinuclear intracytoplasmic filaments. Slender long microvilli projecting into the lumina were also characteristic. Basal laminae were occasionally present around the acini. The findings suggested that the tumor was of mesenchymal origin, closely related to synovial sarcoma.
对一名24岁白人女性上外侧阴道黏膜出现的恶性肿瘤进行了光镜和电镜研究，该肿瘤在文献中尚无描述。肿瘤主要部分为上皮样，形成管状或腺泡状结构。在周边，肿瘤细胞更呈梭形，形成类似纤维肉瘤的片状结构。肿瘤细胞偶尔含有对黏液卡红、阿尔辛蓝和PAS染色呈阳性的物质，形成腺泡的细胞巢被网状纤维包围。肿瘤超微结构由单一类型的细胞组成，具有大的细胞质空泡和偶尔的核周胞质细丝。伸入管腔的细长微绒毛也是其特征。腺泡周围偶尔可见基膜。这些发现提示该肿瘤起源于间叶组织，与滑膜肉瘤密切相关。
