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基于离子交换理论的软骨物理化学性质

Physicochemical properties of cartilage in the light of ion exchange theory.

作者信息

Maroudas A

出版信息

Biophys J. 1968 May;8(5):575-95. doi: 10.1016/S0006-3495(68)86509-9.

DOI:10.1016/S0006-3495(68)86509-9
PMID:5699797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1367401/
Abstract

Ion exchange theory has been applied to articular cartilage. Relationships were derived between permeability, diffusivity, electrical conductivity, and streaming potential. Systematic measurements were undertaken on these properties. Experimental techniques are described and data tabulated. Theoretical correlations were found to hold within the experimental error. The concentration of fixed negatively-charged groups in cartilage was shown to be the most important parameter. Fixed charge density was found to increase with distance from the articular surface and this variation was reflected in the other properties.

摘要

离子交换理论已应用于关节软骨。得出了渗透率、扩散率、电导率和流动电位之间的关系。对这些特性进行了系统测量。描述了实验技术并列出了数据。发现理论相关性在实验误差范围内成立。结果表明,软骨中固定负电荷基团的浓度是最重要的参数。发现固定电荷密度随距关节表面距离的增加而增加,这种变化反映在其他特性中。

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本文引用的文献

1
Distribution of acid glycosaminoglycans in human articular cartilage.酸性糖胺聚糖在人体关节软骨中的分布
Nature. 1967 Sep 23;215(5108):1376-8. doi: 10.1038/2151376a0.