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抗雌激素对小鼠睾酮刺激的攻击行为的抑制作用。

Anti-estrogen inhibition of testosterone-stimulated aggression in mice.

作者信息

Luttge W G

出版信息

Experientia. 1979 Feb 15;35(2):273-4. doi: 10.1007/BF01920660.

DOI:10.1007/BF01920660
PMID:570511
Abstract

Testosterone-stimulated intermale aggression in castrated mice can be reversibly inhibited by anti-estrogen administration suggesting that estrogen formation and actions in the brain may be required for testosterone's behavioral actions.

摘要

在去势小鼠中，睾酮刺激的雄性间攻击行为可通过给予抗雌激素而被可逆性抑制，这表明大脑中雌激素的生成及作用可能是睾酮产生行为效应所必需的。

相似文献

1
Anti-estrogen inhibition of testosterone-stimulated aggression in mice.抗雌激素对小鼠睾酮刺激的攻击行为的抑制作用。
Experientia. 1979 Feb 15;35(2):273-4. doi: 10.1007/BF01920660.
2
The effect of the antiestrogen CI-628 on androgen-induced aggressive behavior in castrated male mice.抗雌激素CI-628对去势雄性小鼠雄激素诱导的攻击行为的影响。
Horm Behav. 1979 Jun;12(3):205-10. doi: 10.1016/0018-506x(79)90002-3.
3
The effects of the antiestrogen CI-628 on sexual behavior activated by androgen or estrogen in quail.抗雌激素CI-628对鹌鹑中由雄激素或雌激素激活的性行为的影响。
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Blockade of testosterone-maintained intermale fighting in albino laboratory mice by an aromatization inhibitor.一种芳香化酶抑制剂对白化病实验小鼠中睾酮维持的雄性间争斗行为的阻断作用。
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Effects of anti-estrogens on testosterone stimulated male sexual behavior and peripheral target tissues in the castrate male rat.抗雌激素对去势雄性大鼠睾酮刺激的雄性性行为及外周靶组织的影响。
Physiol Behav. 1975 Jun;14(6):839-46. doi: 10.1016/0031-9384(75)90079-7.
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Antiestrogens: effects of tamoxifen, nafoxidine, and CI-628 on sexual behavior, cytoplasmic receptors, and nuclear binding of estrogen.抗雌激素：他莫昔芬、萘福昔定和CI-628对性行为、细胞质受体及雌激素核结合的影响
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Estrogen receptor in rabbit ovaries and effects of antiestrogen on progesterone production.
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Embryonic exposure to an antiestrogen masculinizes behavior of female quail.胚胎期接触抗雌激素会使雌性鹌鹑的行为雄性化。
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Effects of intracranial implants of testosterone propionate on intermale aggression in the castrated male mouse.
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Biological potency and uterine estrogen receptor interactions of the metabolites of the antiestrogens CI628 and U23,469.
Endocrinology. 1981 Jan;108(1):164-72. doi: 10.1210/endo-108-1-164.

引用本文的文献

1
Agonistic behavior in males and females: effects of an estrogen receptor beta agonist in gonadectomized and gonadally intact mice.雄性和雌性的攻击行为：雌激素受体β激动剂对去势和未去势小鼠的影响。
Psychoneuroendocrinology. 2010 Aug;35(7):1008-22. doi: 10.1016/j.psyneuen.2010.01.002. Epub 2010 Feb 2.
2
Distribution of aromatase-immunoreactive cells in the mouse forebrain.芳香化酶免疫反应性细胞在小鼠前脑的分布。
Cell Tissue Res. 1991 Jan;263(1):71-9. doi: 10.1007/BF00318401.
3
Recent advances in studies on estrogen biosynthesis.雌激素生物合成的研究新进展

本文引用的文献

1
Estrogen-activated sexual behavior in male rats.
Horm Behav. 1973 Sep;4(3):247-56. doi: 10.1016/0018-506x(73)90009-3.
2
Androgen-induced agonistic behavior in castrate male Swiss-Webster mice: comparison of four naturally occurring androgens.去势雄性瑞士-韦伯斯特小鼠中雄激素诱导的攻击行为：四种天然存在的雄激素的比较
Behav Biol. 1973 Jun;8(6):725-32. doi: 10.1016/s0091-6773(73)80114-2.
3
Activation and inhibition of isolation induced inter-male fighting behavior in castrate male CD-1 mice treated with steroidal hormones.
Horm Behav. 1972 Mar;3(1):71-81. doi: 10.1016/0018-506x(72)90009-8.
4
J Endocrinol Invest. 1979 Oct-Dec;2(4):445-60. doi: 10.1007/BF03349349.
Regional and subcellular [3h]estradiol localization in selected brain regions and pituitary of female mice: effects of unlabeled estradiol and various anti-hormones.雌性小鼠特定脑区和垂体中[3h]雌二醇的区域及亚细胞定位：未标记雌二醇和各种抗激素的影响。
Brain Res. 1976 Mar 12;104(2):273-81. doi: 10.1016/0006-8993(76)90619-3.
5
Effects of anti-estrogens on testosterone stimulated male sexual behavior and peripheral target tissues in the castrate male rat.抗雌激素对去势雄性大鼠睾酮刺激的雄性性行为及外周靶组织的影响。
Physiol Behav. 1975 Jun;14(6):839-46. doi: 10.1016/0031-9384(75)90079-7.
6
Maintenance of male sexual behavior by combined treatment with oestrogen and dihydrotestosterone in CD-1 mice.雌激素与双氢睾酮联合治疗维持CD-1小鼠的雄性性行为
J Endocrinol. 1975 Aug;66(2):257-62. doi: 10.1677/joe.0.0660257.
7
Synergistic effect of estradiol benzoate and dihydrotestosterone on aggression in mice.苯甲酸雌二醇和二氢睾酮对小鼠攻击性的协同作用。
Horm Behav. 1976 Dec;7(4):391-400. doi: 10.1016/0018-506x(76)90010-6.
8
Effect of some antiestrogens and aromatase inhibitors on androgen induced sexual behavior in castrated male rats.某些抗雌激素和芳香化酶抑制剂对去势雄性大鼠雄激素诱导性行为的影响。
Horm Behav. 1976 Sep;7(3):353-63. doi: 10.1016/0018-506x(76)90040-4.
9
The effects of an inhibitor of aromatization (1,4,6-androstatriene-3,17-dione) and an anti-estrogen (Cl-628) on in vivo formed testosterone metabolites recovered from neonatal rat brain tissues and purified cell nuclei. Implications for sexual differentiation of the rat brain.
Brain Res. 1977 Jun 3;128(1):176-81. doi: 10.1016/0006-8993(77)90247-5.
10
The formation of estrogens by central neuroendocrine tissues.中枢神经内分泌组织雌激素的形成。
Recent Prog Horm Res. 1975;31:295-319. doi: 10.1016/b978-0-12-571131-9.50012-8.