Fisher M A, Shahani B T, Young R R
Neurology. 1979 Jan;29(1):45-50. doi: 10.1212/wnl.29.1.45.
Blink reflexes were obtained in a total of 34 different patients with cerebrovascular lesions; 28 were studied within 1 week of the ictus and 11 were eventually restudied. In 13, the latency of the first component of the reflex on the clinically involved side was significantly delayed (greater than 1.5 msec). This was an acute phenomenon that usually resolved within the first week after the ictus, correlated clinically with the severity of the hemiparesis and decrease in tone, and may be seen with lesions restricted to the pyramidal tract. The second component was absent in 17 of 34 patients during the early phase after stroke, and was associated with a decreased corneal response. These changes, which reflect decreased excitability of certain brainstem structures (rather than a lesion within those structures), are therefore potentially important for documenting CNS pathophysiology.
共对34例脑血管病变患者进行了瞬目反射检查；其中28例在发病1周内接受检查，11例最终进行了复查。13例患者患侧反射第一成分的潜伏期显著延迟（超过1.5毫秒）。这是一种急性现象，通常在发病后第一周内缓解，临床上与偏瘫的严重程度和肌张力降低相关，并且在局限于锥体束的病变中也可出现。34例患者中有17例在卒中早期第二成分缺失，且与角膜反射减弱有关。因此，这些反映某些脑干结构兴奋性降低（而非这些结构内病变）的变化，对于记录中枢神经系统病理生理学具有潜在重要意义。
