Sharetskiĭ A N, Tsygankov A P, Tsygankova V A
Biull Eksp Biol Med. 1979 Mar;87(3):260-3.
Accumulation of erythropoietic, granulopoietic cell elements, a change in the ration and absolute count of the T, B cells, and "null" lymphocytes, as well as a sharp inhibition of primary immune response were found in the spleen of CBA mice treated with antierythrocyte sera. The inductive phase of immunogenesis proved to be sensitive to the action of antierythrocyte sera. The data obtained apparently demonstrated the existence of a functional relationship between the immunocompetent spleen cells and their non-lymphoid hemopoietic microenvironment.
在用抗红细胞血清处理的CBA小鼠脾脏中，发现有红细胞生成、粒细胞生成细胞成分的蓄积，T、B细胞及“无标记”淋巴细胞的比例和绝对计数发生改变，以及初级免疫反应受到显著抑制。免疫发生的诱导期被证明对抗红细胞血清的作用敏感。所获得的数据显然表明免疫活性脾细胞与其非淋巴造血微环境之间存在功能关系。
