[来自胎盘、流产及供血者血液中免疫球蛋白的促性腺活性]

[Gonadotropic activity of the immunoglobulins from placental, abortion and donor blood].

作者信息

Minakova L V, Gencheva G P, Kasatskaia L K

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1979 Mar(3):66-71.

Abstract

Gonadotropic activity of 106 series of immunoglobulin preparations obtained in the USSR and-the People's Republic of Bulgaria was studied. In difference from donor immunoglobulins, all the preparations of placental materials were contaminated with chorionic gonadotropin. Gonadotropin content in the immunoglobulins made of abortion serum was 2--7 times greater than in the preparations from the retoplacental serum and the placental extracts. The mean results of gonadotropin content in the immunoglobulins obtained by biological studies differed from those obtained from the investigations by immunological methods since the mentioned methods apparently characterized different properties of the hormonal molecule.

摘要

对苏联和保加利亚人民共和国获得的106批免疫球蛋白制剂的促性腺活性进行了研究。与供体免疫球蛋白不同，所有胎盘物质制剂均被绒毛膜促性腺激素污染。流产血清制成的免疫球蛋白中促性腺激素含量比胎盘后血清和胎盘提取物制成的制剂高2至7倍。生物学研究获得的免疫球蛋白中促性腺激素含量的平均结果与免疫学法研究获得的结果不同，因为上述方法显然表征了激素分子的不同特性。