Blokhina I N, Kiseleva I A, Anastasiev V V, Savkina M A
Zh Mikrobiol Epidemiol Immunobiol. 1985 Feb(2):65-8.
Inclusion of an additional treatment of the products obtained at centrifugation stages b1 and b13 with activated bentonite and aluminium hydroxide into the alcohol method for the production of immunoglobulin from placental and abortion blood permits obtaining preparations with lowered content of proteolytic enzymes and thermostable acid phosphatase, free from chorionic gonadotropin and blood pigment. The treatment of the final preparation with DEAE cellulose removes blood group antigens from immunoglobulins. The preparations obtained by this method have been shown to meet the requirements for immunoglobulins imposed by technological specifications.
在从胎盘血和流产血中生产免疫球蛋白的酒精法中，加入用活性膨润土和氢氧化铝对在离心阶段b1和b13获得的产物进行额外处理，能够得到蛋白水解酶和热稳定酸性磷酸酶含量降低、不含绒毛膜促性腺激素和血色素的制剂。用DEAE纤维素对最终制剂进行处理可去除免疫球蛋白中的血型抗原。已证明通过该方法获得的制剂符合技术规范对免疫球蛋白的要求。
