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Perinatal methadone addiction affects brain synaptic development of biogenic amine systems in the rat.

作者信息

Slotkin T A, Whitmore W L, Salvaggio M, Seidler F J

出版信息

Life Sci. 1979 Mar 26;24(13):1223-9. doi: 10.1016/0024-3205(79)90059-6.

DOI:10.1016/0024-3205(79)90059-6
PMID:571949
Abstract
摘要

相似文献

1
Perinatal methadone addiction affects brain synaptic development of biogenic amine systems in the rat.围产期美沙酮成瘾会影响大鼠生物胺系统的脑突触发育。
Life Sci. 1979 Mar 26;24(13):1223-9. doi: 10.1016/0024-3205(79)90059-6.
2
Development of central and peripheral catecholaminergic systems in rats addicted perinatally to methadone.围产期对美沙酮成瘾大鼠中枢和外周儿茶酚胺能系统的发育
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3
Methadone inhibits serotonin and norephinephrine uptake into rat brain synaptosomes and synaptic vesicles in vitro but not in vivo.美沙酮在体外可抑制5-羟色胺和去甲肾上腺素摄取进入大鼠脑突触体和突触小泡，但在体内则无此作用。
Eur J Pharmacol. 1978 Jun 15;49(4):357-62. doi: 10.1016/0014-2999(78)90309-6.
4
Effect of maternal methadone addiction on offspring in rats.母体美沙酮成瘾对大鼠后代的影响。
Arch Int Pharmacodyn Ther. 1977 Aug;228(2):300-3.
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Development of polyamine and biogenic amine systems in brains and hearts of neonatal rats given dexamethasone: role of biochemical alterations in cellular maturation for producing deficits in ontogeny of neurotransmitter levels, uptake, storage and turnover.给予地塞米松的新生大鼠脑和心脏中多胺和生物胺系统的发育：生化改变在细胞成熟中对神经递质水平、摄取、储存和周转个体发生缺陷产生的作用。
J Pharmacol Exp Ther. 1982 Jun;221(3):686-93.
6
Taurine in developing rat brain: subcellular distribution and association with synaptic vesicles of [35 S] taurine in maternal, fetal and neonatal rat brain.
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Effect of chronic maternal methadone exposure on perinatal development.
Biol Neonate. 1977;31(5-6):271-82. doi: 10.1159/000240975.
8
Effects of maternal methadone administration on ornithine decarboxylase in brain and heart of the offspring: relationships of enzyme activity to dose and to growth impairment in the rat.母体给予美沙酮对后代脑和心脏中鸟氨酸脱羧酶的影响：大鼠中酶活性与剂量及生长发育受损的关系
Life Sci. 1980 Mar 17;26(11):861-7. doi: 10.1016/0024-3205(80)90348-3.
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Body and organ development of young rats maternally exposed to methadone.
Biol Neonate. 1980;38(3-4):185-96. doi: 10.1159/000241363.
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Perinatal methadone exposure and brain development: a biochemical study.
J Neurochem. 1978 Jul;31(1):49-54. doi: 10.1111/j.1471-4159.1978.tb12431.x.

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Methadone directly impairs central nervous system cells in vitro.美沙酮在体外直接损害中枢神经系统细胞。
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Methadone alters transcriptional programs associated with synapse formation in human cortical organoids.美沙酮改变了与人类皮质类器官中突触形成相关的转录程序。
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The effects of maternally administered methadone, buprenorphine and naltrexone on offspring: review of human and animal data.美沙酮、丁丙诺啡和纳曲酮对母婴的影响：人类和动物数据综述。
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Effects of prenatal morphine on hypothalamic metabolism of neurotransmitters and gonadal and adrenal activities, during the early postnatal period in the rat.产前吗啡对大鼠出生后早期下丘脑神经递质代谢以及性腺和肾上腺活动的影响。
Neurochem Res. 1996 Jun;21(6):723-32. doi: 10.1007/BF02527731.
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Morphine alters astrocyte growth in primary cultures of mouse glial cells: evidence for a direct effect of opiates on neural maturation.吗啡改变小鼠神经胶质细胞原代培养物中星形胶质细胞的生长：阿片类药物对神经成熟有直接影响的证据。
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