Prell H H, Auer J, Soska J, Hava P
Mol Gen Genet. 1984;198(2):105-9. doi: 10.1007/BF00328708.
Salmonella phage mutants P22 cir4-1, P22 cir5-1 and P22 cir6-1 at 37 degrees C form more or less clear plaques. The mutants complement each other and clear mutations of the immC region (Prell et al. 1983). The mutants exhibit a strongly reduced frequency of lysogenisation, but form stable prophages. The low frequency of lysogenisation of P22 cir5-1 and of P22 cir6-1 is suppressed by an additional ant- mutation. Similarly, about 50% of turbid plaque revertants of both mutants carry ant- suppressor mutations. This suggests interference by the cir5-1 and cir6-1 mutations with the expression of gene ant. In contrast, the cir4-1 mutation seems not to interfere with ant expression, the latent periods of P22 cir4-1 and P22 cir5-1 are reduced and extended, respectively. The geneticly related Salmonella phage L carries a gene able to complement P22 cir4-1.
沙门氏菌噬菌体突变体P22 cir4-1、P22 cir5-1和P22 cir6-1在37摄氏度时形成或多或少清晰的噬菌斑。这些突变体相互互补，并消除了immC区域的突变（普雷尔等人，1983年）。这些突变体表现出溶原化频率大幅降低，但能形成稳定的原噬菌体。P22 cir5-1和P22 cir6-1的低溶原化频率被额外的ant-突变所抑制。同样，这两种突变体的约50%浑浊噬菌斑回复体携带ant-抑制突变。这表明cir5-1和cir6-1突变干扰了ant基因的表达。相比之下，cir4-1突变似乎不干扰ant表达，P22 cir4-1和P22 cir5-1的潜伏期分别缩短和延长。遗传相关的沙门氏菌噬菌体L携带一个能够互补P22 cir4-1的基因。
