Blanchard D C, Blanchard R J, Lee E M, Nakamura S
J Comp Physiol Psychol. 1979 Apr;93(2):378-90. doi: 10.1037/h0077562.
Rats with anterior septal lesions showed a pattern of consistent enhancement of defensive behaviors normally elicited by threatening conspecifics, with no enhancement of attack or general reactivity. Further division of this group indicated that damage to sites anterior and ventral to the septal area, sites previously implicated in the "septal syndrome," produces maximal effect on these behaviors. When amygdala lesions are combined with septal damage this enhanced defensive responding is almost completely eliminated. These results were interpreted as indicating that the septal syndrome represents hyperdefensiveness to conspecific threat stimuli rather than aggression or increased general reactivity, and that amygdaloid mechanisms are also involved in the regulation of conspecific defensive behaviors.
患有前隔区损伤的大鼠表现出一种模式，即通常由威胁性同种个体引发的防御行为持续增强，而攻击行为或一般反应性没有增强。对该组进一步细分表明，隔区前方和腹侧部位的损伤，即先前与“隔区综合征”相关的部位，对这些行为产生最大影响。当杏仁核损伤与隔区损伤相结合时，这种增强的防御反应几乎完全消除。这些结果被解释为表明隔区综合征代表对同种威胁刺激的过度防御，而不是攻击或一般反应性增加，并且杏仁核机制也参与同种防御行为的调节。
