Ho S U, Berenberg R A, Kim K S, Dal Canto M C
Neurology. 1979 Aug;29(8):1161-5. doi: 10.1212/wnl.29.8.1161.
Sequential computerized tomography (CT) was performed on a patient with seizures and an organic mental syndrome. Cerebral sarcoidosis was subsequently diagnosed on the basis of noncaseating granulomas in three organ systems. Cranial nerve palsies, hypothalamic dysfunction, and widespread disease were absent. An unusual neuroradiologic sequence of events indicated focal and asymmetric hydrocephalus, mass effect, ependymitis, diffuse breakdown of the blood-brain barrier, and periventricular white matter destruction. These findings have not been previously described together in a patient with sarcoid. With the advent of noninvasive CT, it is possible to perform serial investigations of encephalopathies of obscure origin. Findings similar to those in the present case should prompt a thorough search for subclinical systemic involvement by sarcoid.
对一名患有癫痫和器质性精神综合征的患者进行了连续计算机断层扫描（CT）。随后根据三个器官系统中的非干酪样肉芽肿诊断为脑结节病。未出现颅神经麻痹、下丘脑功能障碍和广泛病变。一系列不寻常的神经放射学事件显示为局灶性和不对称性脑积水、占位效应、室管膜炎、血脑屏障弥漫性破坏以及脑室周围白质破坏。这些发现此前尚未在结节病患者中一起描述过。随着无创CT的出现，可以对病因不明的脑病进行系列研究。与本病例相似的发现应促使彻底检查是否存在结节病的亚临床全身受累情况。
