Savoldi F, Tartara A, Bo P
Farmaco Sci. 1979 Jun;34(6):526-34.
The eeg changes induced by acute administration in rabbits of dopamine-agonist drugs (bromocriptine, apomorphine, piribedil) were studied. We examined the spontaneous electric activity of cortex and deep structures, the electric excitability thresholds and the action of these drugs in "cerveau isolé" rabbit. Eeg findings were correlated with behavioural reactions. The modes of action and the probable double point of attack of the drugs at the CNS are discussed.
研究了多巴胺激动剂药物（溴隐亭、阿扑吗啡、吡贝地尔）急性给药诱导家兔产生的脑电图变化。我们检测了家兔大脑皮质和深部结构的自发电活动、电兴奋性阈值以及这些药物在“孤立脑”家兔中的作用。脑电图结果与行为反应相关。讨论了这些药物在中枢神经系统的作用方式和可能的双重作用位点。
