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成人和胚胎对有机磷酸酯类农药的反应:谷硫磷。

Adult and embryo responses to organophosphate pesticides: azodrin.

作者信息

Schom C B, Abbott U K, Walker N E

出版信息

Poult Sci. 1979 Jan;58(1):60-6. doi: 10.3382/ps.0580060.

DOI:10.3382/ps.0580060
PMID:572969
Abstract

Azodrin was applied to adult embryo chickens, Chukar Partridge, and Bobwhite Quail. Chronic exposure of adult birds to Azodrin mixed in their feed indicated that no a priori predictions could be made about one species based on the results of another; each had a different no effect (MACT) level. The chickens were between 25 and 100 ppm, the Chukar Partridge 5 and 25 ppm, and the Bobwhite quail less than 1.25 ppm. The chicken adults were most resistant, and the quail were least resistant to chronic exposure to Azodrin. Yolk-injected Azodrin caused the embryos of all three species to develop abnormally. The chicken and Chukar embryos developed a generalized achondroplasia, the quail were amuscular, only. In general, the 3 day quail embryos were most resistant to injected Azodrin and the chicken embryo least resistant. The relationship between adult and embryo response was negative.

摘要

对成年胚胎鸡、石鸡和美国鹌鹑使用了久效磷。成年鸟类长期接触饲料中混合的久效磷表明,无法根据一个物种的结果对另一个物种进行先验预测;每个物种都有不同的无影响(最大可接受浓度)水平。鸡的无影响水平在25至100 ppm之间,石鸡为5至25 ppm,美国鹌鹑小于1.25 ppm。成年鸡对久效磷的慢性暴露最具抗性,而鹌鹑最不具抗性。向卵黄中注射久效磷会导致所有这三个物种的胚胎发育异常。鸡和石鸡胚胎出现全身性软骨发育不全,鹌鹑仅出现肌肉发育不全。一般来说,3日龄鹌鹑胚胎对注射的久效磷最具抗性,鸡胚胎最不具抗性。成年和胚胎反应之间的关系是负相关的。

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