Schom C B, Abbott U K
Teratology. 1977 Feb;15(1):81-7. doi: 10.1002/tera.1420150111.
The effect of Azodrin on avian development was studied using a bobwhite quail line and two chicken lines--a single comb White Leghorn (SCWL) and an Australorp line. The bobwhite quail embryos did not respond to injections of Azodrin until stages 22 to 23 (6 days of incubation); the SCWL embryos, not until stage 18 (3 days of incubation) with increasing susceptibility through stage 20. The threshold concentration, at stage 19, for the SCWL was 0.4 mg/kg, for the Australorp, less. Within one hour of treatment stage-20 embryo shape was altered. There was, however, no immediate response from embryos treated earlier. The effect appeared as a reduced growth rate in the cervical flexure, and may be mediated by interference with the normal energy balance. The response, once initiated, was continuous through 10 days of incubation.
使用一种北美鹑品系和两种鸡品系——单冠白来航鸡（SCWL）和澳洲黑鸡品系，研究了谷硫磷对禽类发育的影响。北美鹑胚胎直到第22至23阶段（孵化6天）才对谷硫磷注射有反应；SCWL胚胎直到第18阶段（孵化3天）才有反应，且在第20阶段敏感性不断增加。在第19阶段，SCWL的阈值浓度为0.4毫克/千克，澳洲黑鸡的阈值浓度更低。在处理第20阶段胚胎的一小时内，胚胎形状发生改变。然而，早期处理的胚胎没有立即出现反应。这种影响表现为颈部弯曲处生长速率降低，可能是由对正常能量平衡的干扰介导的。一旦开始反应，在孵化的10天内会持续存在。
