2-（氨甲基）-2-脱羧前列地尔F2α型类似物
2-(Aminomethyl)-2-decarboxyprostaglandin F2 alpha type analogs.
作者信息
Nelson N A, Sih J C, Jackson R W, Miller W L, Cornette J C
出版信息
Prostaglandins. 1979 Mar;17(3):441-9. doi: 10.1016/s0090-6980(79)80012-x.
PMID:572982
Abstract
The 2-(aminomethyl)-2-decarboxy analogs of prostaglandin F2 alpha (PGF2 alpha), (15S)-15-methyl-PGF2 alpha, 16-phenoxy-omega-tetranor-PGF2 alpha and 16,16-dimethyl-PGF2 alpha were synthesized. The amino analogs closely resemble the parent PGF2 alpha compounds as antifertility agents in the hamster.
摘要
合成了前列腺素F2α（PGF2α）的2-（氨甲基）-2-脱羧类似物、（15S）-15-甲基-PGF2α、16-苯氧基-ω-四降-PGF2α和16,16-二甲基-PGF2α。在仓鼠中，这些氨基类似物作为抗生育剂与母体PGF2α化合物非常相似。
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