• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Bovine superoxide dismutase and copper ions potentiate the bactericidal effect of autoxidizing cysteine.牛超氧化物歧化酶和铜离子可增强自氧化半胱氨酸的杀菌效果。
Appl Environ Microbiol. 1979 Jul;38(1):29-34. doi: 10.1128/aem.38.1.29-34.1979.
2
Bactericidal effect of cysteine exposed to atmospheric oxygen.暴露于大气氧中的半胱氨酸的杀菌作用。
Appl Environ Microbiol. 1979 Mar;37(3):383-90. doi: 10.1128/aem.37.3.383-390.1979.
3
Bactericidal effect of anaerobic broth exposed to atmospheric oxygen tested on Peptostreptococcus anaerobius.在厌氧消化链球菌上测试暴露于大气氧的厌氧肉汤的杀菌效果。
J Clin Microbiol. 1977 Aug;6(2):117-23. doi: 10.1128/jcm.6.2.117-123.1977.
4
Metabolic inhibition of Peptostreptococcus anaerobius decreases the bactericidal effect of hydrogen peroxide.厌氧消化链球菌的代谢抑制降低了过氧化氢的杀菌效果。
Antimicrob Agents Chemother. 1981 Dec;20(6):726-30. doi: 10.1128/AAC.20.6.726.
5
Transition metals potentiate paraquat toxicity.过渡金属会增强百草枯的毒性。
Free Radic Res Commun. 1985;1(2):79-88. doi: 10.3109/10715768509056540.
6
Hydrogen peroxide and superoxide radical formation in anaerobic broth media exposed to atmospheric oxygen.暴露于大气氧中的厌氧肉汤培养基中过氧化氢和超氧阴离子自由基的形成。
Appl Environ Microbiol. 1978 Aug;36(2):223-9. doi: 10.1128/aem.36.2.223-229.1978.
7
Bactericidal and cytotoxic effects of hypothiocyanite-hydrogen peroxide mixtures.次硫氰酸盐-过氧化氢混合物的杀菌及细胞毒性作用
Infect Immun. 1984 Jun;44(3):581-6. doi: 10.1128/iai.44.3.581-586.1984.
8
The production of free radicals during the autoxidation of cysteine and their effect on isolated rat hepatocytes.半胱氨酸自氧化过程中自由基的产生及其对分离的大鼠肝细胞的影响。
Biochim Biophys Acta. 1982 Oct 28;719(1):24-31. doi: 10.1016/0304-4165(82)90302-6.
9
Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage.半胱氨酸的翻译后修饰可保护 Cu/Zn-超氧化物歧化酶免受氧化损伤。
Biochemistry. 2013 Sep 10;52(36):6137-44. doi: 10.1021/bi4006122. Epub 2013 Aug 26.
10
Reaction of bovine-liver copper-zinc superoxide dismutase with hydrogen peroxide. Evidence for reaction with H2O2 and HO2- leading to loss of copper.牛肝铜锌超氧化物歧化酶与过氧化氢的反应。与H2O2和HO2-反应导致铜流失的证据。
Eur J Biochem. 1989 Apr 1;180(3):569-75. doi: 10.1111/j.1432-1033.1989.tb14683.x.

引用本文的文献

1
Presence of hydrogen peroxide in media used for cultivation of Neisseria gonorrhoeae.用于淋病奈瑟菌培养的培养基中过氧化氢的存在情况。
J Clin Microbiol. 1982 Jan;15(1):103-8. doi: 10.1128/jcm.15.1.103-108.1982.
2
Potentiation by sulfide of hydrogen peroxide-induced killing of Escherichia coli.硫化氢对过氧化氢诱导的大肠杆菌杀伤作用的增强效应
Infect Immun. 1985 Sep;49(3):538-43. doi: 10.1128/iai.49.3.538-543.1985.
3
Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine.同型半胱氨酸通过铜催化产生过氧化氢导致内皮细胞损伤。
J Clin Invest. 1986 Apr;77(4):1370-6. doi: 10.1172/JCI112442.
4
Role of keto acids and reduced-oxygen-scavenging enzymes in the growth of Legionella species.酮酸和低氧清除酶在军团菌属生长中的作用。
J Clin Microbiol. 1986 Jan;23(1):33-42. doi: 10.1128/jcm.23.1.33-42.1986.

本文引用的文献

1
The Role of Peroxide in the Biological Effects of Irradiated Broth.过氧化物在辐照肉汤生物学效应中的作用。
J Bacteriol. 1948 Jul;56(1):51-7.
2
A growth-inhibitory effect on Shigella dysenteriae which occurs with some batches of nutrient agar and is associated with the production of peroxide.某些批次的营养琼脂对痢疾志贺菌具有生长抑制作用，且与过氧化物的产生有关。
J Gen Microbiol. 1950 May;4(2):270-6. doi: 10.1099/00221287-4-2-270.
3
ACCELERATING EFFECT OF COPPER ION ON THE REACTIVATION OF REDUCED TAKA-AMYLASE A THROUGH CATALYSIS OF THE OXIDATION OF SULFHYDRYL GROUPS.铜离子通过催化巯基氧化对还原型高峰淀粉酶A再活化的加速作用
J Biochem. 1964 Oct;56:344-50. doi: 10.1093/oxfordjournals.jbchem.a127999.
4
Irreversible reaction of 3-amino-1:2:4-triazole and related inhibitors with the protein of catalase.3-氨基-1:2:4-三唑及相关抑制剂与过氧化氢酶蛋白的不可逆反应。
Biochem J. 1960 Feb;74(2):339-48. doi: 10.1042/bj0740339.
5
Peroxide formation in bacteriological media.细菌培养基中过氧化物的形成。
Nature. 1956 Sep 15;178(4533):596-7. doi: 10.1038/178596a0.
6
A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids.一种在其他天然存在的氨基酸存在下直接测定半胱氨酸的分光光度法。
Biochem J. 1967 Aug;104(2):627-33. doi: 10.1042/bj1040627.
7
Catalase-aminotriazole method for measuring secretion of hydrogen peroxide by microorganisms.用于测量微生物过氧化氢分泌量的过氧化氢酶-氨基三唑法。
J Bacteriol. 1969 May;98(2):543-6. doi: 10.1128/jb.98.2.543-546.1969.
8
An enzyme-based theory of obligate anaerobiosis: the physiological function of superoxide dismutase.基于酶的专性厌氧菌理论：超氧化物歧化酶的生理功能。
Proc Natl Acad Sci U S A. 1971 May;68(5):1024-7. doi: 10.1073/pnas.68.5.1024.
9
Oxygen metabolism in Lactobacillus plantarum.植物乳杆菌中的氧代谢
J Bacteriol. 1974 Jan;117(1):166-9. doi: 10.1128/jb.117.1.166-169.1974.
10
The copper catalyzed oxidation of cysteine to cystine.铜催化的半胱氨酸氧化为胱氨酸的反应。
Arch Biochem Biophys. 1969 Mar;130(1):354-61. doi: 10.1016/0003-9861(69)90044-7.

牛超氧化物歧化酶和铜离子可增强自氧化半胱氨酸的杀菌效果。

Bovine superoxide dismutase and copper ions potentiate the bactericidal effect of autoxidizing cysteine.

作者信息

Nyberg G K, Granberg G P, Carlsson J

出版信息

Appl Environ Microbiol. 1979 Jul;38(1):29-34. doi: 10.1128/aem.38.1.29-34.1979.

DOI:10.1128/aem.38.1.29-34.1979
PMID:573589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC243430/
Abstract

When cysteine is oxidized by oxygen, hydrogen peroxide is formed, and hydrogen peroxide is very toxic to Peptostreptococcus anaerobius VPI 4330-1. Native and inactivated superoxide dismutase increased the rate of oxidation of cysteine and thereby potentiated the toxic effect of cysteine. A similar increase in the rate of oxidation of cysteine and in the toxicity of cysteine was obtained with Cu2+.

摘要

当半胱氨酸被氧气氧化时，会生成过氧化氢，而过氧化氢对厌氧消化链球菌VPI 4330-1具有很强的毒性。天然和失活的超氧化物歧化酶会提高半胱氨酸的氧化速率，从而增强半胱氨酸的毒性作用。用Cu2+也能使半胱氨酸的氧化速率和毒性产生类似的增加。